학술논문

Investigating the therapeutic properties of elicited Lab Lab sprouts: insights into the antihypertensive and antidiabetic effects
Document Type
Original Paper
Source
Journal of Food Measurement and Characterization. 18(5):3378-3390
Subject
Bioactive compounds
Elicitation treatments
ACE inhibitory activity
α Amylase inhibitory activity
GABA
Lablab sprout
Language
English
ISSN
2193-4126
2193-4134
Abstract
This study investigates the impact of elicitation on the phytochemical content, antioxidant activity, protein profiles, GABA content, and inhibitory activities against Angiotensin converting enzyme and alpha-amylase of two genotypes of Lab Lab sprouts, GUJ.W.2 and GNIB-22. Elicitation treatments with different substances triggered significant alterations in the sprouts’ metabolic profile, enhancing their potential health benefits. Notably, there were evident changes in phenolic, ascorbic acid, flavonoid, and protein content across different elicited sprouts. Antioxidant activities were examined via DPPH and FRAP assays, GUJ.W.2 variety elicited, and control displayed (~ 30% inhibitory activity) higher antioxidant activity compared to GNIB-22. The GUJ.W.2 samples treated with glutamic acid and GNIB chitosan with lactic acid depicted statistical similarity in FRAP activity. Meanwhile, protein profiling, carried out through SDS-PAGE, suggested intrinsic genetic differences in protein synthesis mechanisms and metabolic activities between the genotypes. Furthermore, the elicited sprouts demonstrated high GABA content, a neuroactive amino acid with multiple physiological properties, including antihypertensive and antidiabetic effects. Remarkably, the elicited sprouts also exhibited enhanced ACE inhibitory activity (~ 80%), indicating potential hypertension management properties. Contrarily, the control group sprouts of GNIB- 22 showed higher alpha amylase inhibitory activity (~ 64%), denoting potential antidiabetic effects. The study demonstrates that the elicitation of Lab Lab seeds significantly enhances the nutritional and health-promoting properties of the sprouts. These findings pave the way for further exploration and potential application of Lab Lab sprouts in functional foods and therapeutic strategies.