학술논문

Successful pregnancy after 10 consecutive failures in a liver transplant patient with advanced kidney failure
Document Type
Original Paper
Source
Journal of Nephrology. 37(3):747-751
Subject
Pregnancy
Liver transplant
Calcineurin inhibitor
Kidney disease
Preeclampsia
Language
English
ISSN
1724-6059
Abstract
We report a successful, albeit complicated pregnancy with a live-born healthy baby at 28 weeks' gestation, after 10 pregnancy failures, in a 39-year-old patient with a history of liver transplantation and chronic kidney disease with hypertension and proteinuria. Multidisciplinary management (obstetrician, nephrologist and hepatology transplant specialist) allowed close monitoring, adaptation of immunosuppressive treatments and strict control of fetal growth. The onset of preeclampsia at 28 weeks' gestation led to a cesarean section, resulting in the birth of a healthy 830 g boy, with subsequent normal development. Following pregnancy, the patient experienced liver transplant rejection, which resolved after adapting immunosuppressive drugs. No deterioration in kidney function was observed in the year following delivery.