부산대학교 도서관

Kidney transplant patients are subject to an increased risk of developing cancer due to immunosuppressive therapy. On the contrary, the incidence of neoplasm on renal graft is low. In the case of graft tumors, a balance must be made between maintaining the functionality of the graft and radical treatment of the tumor. In the case of small tumors, it is possible to perform a nephron-sparing surgery, which allows to treat cancer with low recurrence rates and maintenance of renal function. In this study, we evaluate the management of graft tumors in a single transplant center. We registered three cases of graft tumors per 633 transplantations in a 20-year period with a calculated incidence of 0.47%. In all cases, thanks to a regular follow-up, it was possible to diagnose the neoplasm at an early stage and treat it by a nephron-sparing technique. It was thus possible to ensure the healing from the tumor and preservation of the function of the kidney graft. We report, in fact, a good maintenance of kidney function and the absence of recurrence at a long follow-up.