학술논문
Synthesis and antitumor activity of 7-(triazol-1-yl)pyrroloallocolchicine derivatives
Document Type
Original Paper
Author
Source
Russian Chemical Bulletin. June 2015 64(6):1362-1368
Subject
Language
English
ISSN
1066-5285
1573-9171
1573-9171
Abstract
The cycloaddition of acetylene derivatives of azido-substituted pyrroloallocolchicines afforded 7-(triazol-1-yl)pyrroloallocolchicines. The synthesized compounds exhibit considerable cytotoxicity and apoptosis-inducing activity against Nalm 6 human leukemia cells.