학술논문
COVID-19: vaccination vs. hospitalization
Document Type
Original Paper
Author
Uzun, Oguz; Akpolat, Tekin; Varol, Ayhan; Turan, Sema; Bektas, Serife Gokbulut; Cetinkaya, Pelin Duru; Dursun, Mazlum; Bakan, Nurten; Ketencioglu, Burcu Baran; Bayrak, Murat; Baris, Serap Argun; Guner, Rahmet; Gunal, Ozgur; Nural, Serkan; Deniz, Pelin Pinar; Toprak, Oya Baydar; Ozkan, Gulcihan; Gumus, Ayça; Kerget, Ferhan; Ercelik, Merve; Ataoglu, Ozlem; Yuksel, Aycan; Ates, Gungor; Kutsoylu, Oya Eren; Kose, Neslihan; Kizilirmak, Deniz; Keskin, Serdar; Gultekin, Okkes; Coskun, Nilüfer; Yilmaz, Emine Serap; Uslu, Selen; Basyigit, İlknur; Ergan, Begüm; Deveci, Figen; Yakar, Mehmet Nuri; Zuhur, Cigdem; Sagcan, Gulseren; Yuce, Zeynep Ture; Kuluozturk, Mutlu; Sezgin, Mehmet Emin; Sezgin, Esma Nur Aktepe; Havlucu, Yavuz; Cuhadaroglu, Caglar; Kilinc, Oguz; Boyaci, Hasim; Altunay, Hayriye; Akti, Mehmet; Dursun, Zehra Bastepe; Kalem, Ayse Kaya; Isik, Sinem Akkaya; Akyildiz, Levent; Aykac, Nilüfer; Almaz, Mehmet Selim; Kokturk, Nurdan; Itil, Oya
Source
Infection: A Journal of Infectious Diseases. 50(3):747-752
Subject
Language
English
ISSN
0300-8126
1439-0973
1439-0973
Abstract
Objective: Vaccination is the most efficient way to control the coronavirus disease 2019 (COVID-19) pandemic, but vaccination rates remain below the target level in most countries. This multicenter study aimed to evaluate the vaccination status of hospitalized patients and compare two different booster vaccine protocols.Setting: Inoculation in Turkey began in mid-January 2021. Sinovac was the only available vaccine until April 2021, when BioNTech was added. At the beginning of July 2021, the government offered a third booster dose to healthcare workers and people aged > 50 years who had received the two doses of Sinovac. Of the participants who received a booster, most chose BioNTech as the third dose.Methods: We collected data from 25 hospitals in 16 cities. Patients hospitalized between August 1 and 10, 2021, were included and categorized into eight groups according to their vaccination status.Results: We identified 1401 patients, of which 529 (37.7%) were admitted to intensive care units. Nearly half (47.8%) of the patients were not vaccinated, and those with two doses of Sinovac formed the second largest group (32.9%). Hospitalizations were lower in the group which received 2 doses of Sinovac and a booster dose of BioNTech than in the group which received 3 doses of Sinovac.Conclusion: Effective vaccinations decreased COVID-19-related hospitalizations. The efficacy after two doses of Sinovac may decrease over time; however, it may be enhanced by adding a booster dose. Moreover, unvaccinated patients may be persuaded to undergo vaccination.