학술논문

In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
Document Type
article
Source
Química Nova. January 2014 37(10)
Subject
Syngonium podophyllum
Araceae
Isoschaftoside
enzyme inhibition
renal Na+, K+-ATPase
Language
English
ISSN
0100-4042
Abstract
The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.