학술논문

CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion
Document Type
report
Source
Anais Brasileiros de Dermatologia. May 2019 94(3)
Subject
Cholesterol
Ichthyosis
Lovastatin
Language
English
ISSN
0365-0596
Abstract
CHILD syndrome (Congenital Hemidysplasia, Ichthyosiform erythroderma, Limb Defects) is a rare X-linked dominant disease. The authors report a 2-month-old patient presenting with typical features of CHILD syndrome that was treated with a topical solution containing cholesterol and lovastatin, with complete clearance of her CHILD nevus. The changes in skin lipid metabolism that explain the CHILD ichthyosiform nevus and their correction through topical application of cholesterol and lovastatin are discussed.