학술논문
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies
Document Type
article
Author
Source
Genetics and Molecular Biology. January 2009 32(4)
Subject
Language
English
ISSN
1415-4757
Abstract
ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia.