학술논문

Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation
Document Type
article
Source
Revista Brasileira de Hematologia e Hemoterapia. January 2012 34(2)
Subject
hematopoietic cell transplantation
allogeneic
autologous
late complications
screening
prevention
Language
English
ISSN
1516-8484
Abstract
Advances in hematopoietic cell transplantation (HCT) technology and supportive care techniques have led to improvements in long-term survival after HCT. Emerging indications for transplantation, introduction of newer graft sources (e.g. umbilical cord blood) and transplantation of older patients using less intense conditioning regimens have also contributed to an increase in the number of HCT survivors. These survivors are at risk for developing late complications secondary to pre-, periand post-transplant exposures and risk-factors. Guidelines for screening and preventive practices for HCT survivors were published in 2006. An international group of transplant experts was convened in 2011 to review contemporary literature and update the recommendations while considering the changing practice of transplantation and international applicability of these guidelines. This review provides the updated recommendations for screening and preventive practices for pediatric and adult survivors of autologous and allogeneic HCT.