학술논문

Diagnostic approach of eosinophilic spongiosis
Document Type
article
Source
Anais Brasileiros de Dermatologia. November 2019 94(6)
Subject
Diagnosis, differential
Eosinophils
Pemphigoid, bullous
Pemphigus
Skin diseases, vesiculobullous
Language
English
ISSN
0365-0596
Abstract
Eosinophilic spongiosis is a histological feature shared by some distinct inflammatory disorders, and is characterized by the presence of intraepidermal eosinophils associated with spongiosis. Most often, isolated eosinophilic spongiosis indicates the early stages of a subjacent autoimmune bullous dermatosis, such as the pemphigus group and bullous pemphigoid. Herein, the main causes of eosinophilic spongiosis are discussed, as well as the supplementary investigation needed to elucidate its etiology.