학술논문

Acute bacterial meningitis in HIV, pacients in southern Brazil: Curitiba, Paraná, Brazil
Document Type
article
Source
Arquivos de Neuro-Psiquiatria. June 2007 65(2A)
Subject
HIV
AIDS
bacterial meningitis
pneumococcus
central nervous system
cerebrospinal fluid
Language
English
ISSN
0004-282X
Abstract
Acute communitarian bacterial meningitis and AIDS are prevalent infectious disease in Brazil. The objective of this study was to evaluate the frequency of acute communitarian bacterial meningitis in AIDS patients, the clinical and cerebrospinal fluid (CSF) characteristics. It was reviewed the Health Department data from city of Curitiba, Southern Brazil, from 1996 to 2002. During this period, 32 patients with AIDS fulfilled criteria for acute bacterial meningitis, representing 0.84% of the AIDS cases and 1.85% of the cases of bacterial meningitis. S. pneumoniae was the most frequent bacteria isolated. The number of white blood cells and the percentage of neutrophils were higher and CSF glucose was lower in the group with no HIV co-infection (p 0.12; 0.008; 0.04 respectively). Bacteria not so common causing meningitis can occur among HIV infected patients. The high mortality rate among pneumococcus meningitis patients makes pneumococcus vaccination important.