학술논문

Use and outcomes of cerebral embolic protection for transcatheter aortic valve replacement: A US nationwide study
Document Type
article
Source
Catheterization and Cardiovascular Interventions. 98(5)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Transplantation
Stroke
Neurosciences
Brain Disorders
Good Health and Well Being
Aortic Valve
Aortic Valve Stenosis
Hospital Mortality
Humans
Postoperative Complications
Risk Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome
aortic valve disease
embolic protection devices
percutaneous valve therapy
percutaneous intervention
transcatheter valve implantation
Cardiorespiratory Medicine and Haematology
Cardiovascular System & Hematology
Cardiovascular medicine and haematology
Language
Abstract
BackgroundOutcomes data on the use of cerebral embolic protection devices (CPDs) with transcatheter aortic valve replacement (TAVR) remain limited. Previous randomized trials were underpowered for primary outcomes of stroke prevention and mortality.MethodsThe National Inpatient Sample and Nationwide Readmissions Database were queried from 2017 to 2018 to study utilization and inpatient mortality, neurological complications (ischemic stroke, hemorrhagic stroke, and transient ischemic attack), procedural complications, resource utilization, and 30-day readmissions with and without use of CPD. A 1:3 ratio propensity score matched model was created.ResultsAmong 108,315 weighted encounters, CPD was used in 4380 patients (4.0%). Adjusted mortality was lower in patients undergoing TAVR with CPD (1.3% vs. 0.5%, p