학술논문

Building Bonds: Cancer Stem Cells Depend on Their Progeny to Drive Tumor Progression
Document Type
article
Source
Cell Stem Cell. 22(4)
Subject
Biochemistry and Cell Biology
Biomedical and Clinical Sciences
Oncology and Carcinogenesis
Biological Sciences
Rare Diseases
Cancer
Stem Cell Research
Brain Disorders
Stem Cell Research - Nonembryonic - Non-Human
Neurosciences
Regenerative Medicine
Brain Cancer
Stem Cell Research - Nonembryonic - Human
5.2 Cellular and gene therapies
Development of treatments and therapeutic interventions
Adult
Cell Differentiation
Glioblastoma
Glioma
Humans
Neoplastic Stem Cells
Signal Transduction
Medical and Health Sciences
Developmental Biology
Biological sciences
Biomedical and clinical sciences
Language
Abstract
Little is currently known about how cancer stem-like cells (CSCs) interact with their more restricted progeny. In this issue of Cell Stem Cell, Wang et al. (2018) demonstrate a novel bidirectional signaling axis between CSCs and their progeny that is mediated by brain-derived neurotrophic factor and VGF accelerating glioma progression.