학술논문

Tissue States Provide Novel Insights into Attributes that Drive Metastasis
Document Type
article
Author
Source
Cancer Cell. 20(3)
Subject
Biomedical and Clinical Sciences
Oncology and Carcinogenesis
Breast Cancer
Cancer
Neurosciences
Oncology & Carcinogenesis
Biochemistry and cell biology
Oncology and carcinogenesis
Language
Abstract
Recently, in Nature Medicine, Schedin and colleagues define attributes within the involuting postpartum breast microenvironment that promote breast cancer metastasis. Cell invasiveness is controlled by a positive feedback loop involving COX-2 and fibrillar collagen. NSAIDs suppress tumor progression during postpartum involution, potentially providing effective agents for intervention in pregnant women.