학술논문

Maintenance of remission following 2 years of standard treatment then dose reduction with abatacept in patients with early rheumatoid arthritis and poor prognosis
Document Type
article
Source
Annals of the Rheumatic Diseases. 74(3)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Clinical Trials and Supportive Activities
Autoimmune Disease
Clinical Research
Arthritis
Evaluation of treatments and therapeutic interventions
6.1 Pharmaceuticals
Inflammatory and immune system
Abatacept
Adult
Antirheumatic Agents
Arthritis
Rheumatoid
Double-Blind Method
Female
Humans
Immunoconjugates
Induction Chemotherapy
Kaplan-Meier Estimate
Maintenance Chemotherapy
Male
Middle Aged
Prognosis
Recurrence
Remission Induction
Treatment Outcome
DMARDs
Disease Activity
Early Rheumatoid Arthritis
Rheumatoid Arthritis
Treatment
Immunology
Public Health and Health Services
Arthritis & Rheumatology
Clinical sciences
Language
Abstract
ObjectivesTo evaluate maintenance of response while reducing intravenous abatacept dose from ~10 mg/kg to ~5 mg/kg in patients with early rheumatoid arthritis (RA) who achieved disease activity score (DAS)28 (erythrocyte sedimentation rate, ESR)