학술논문

Heart Rate and Outcomes in Hospitalized Patients With Heart Failure With Preserved Ejection Fraction
Document Type
article
Source
Journal of the American College of Cardiology. 70(15)
Subject
Biomedical and Clinical Sciences
Cardiovascular Medicine and Haematology
Heart Disease
Cardiovascular
Aging
Clinical Research
Adrenergic beta-Antagonists
Aged
Aged
80 and over
Female
Follow-Up Studies
Heart Failure
Heart Rate
Hospitalization
Humans
Male
Medicare
Mortality
Outcome and Process Assessment
Health Care
Patient Acuity
Patient Discharge
Patient Readmission
Proportional Hazards Models
Registries
Risk Assessment
Stroke Volume
United States
all-cause mortality
all-cause readmission
atrial fibrillation
beta-blockers
propensity score
Cardiorespiratory Medicine and Haematology
Public Health and Health Services
Cardiovascular System & Hematology
Cardiovascular medicine and haematology
Language
Abstract
BackgroundA lower heart rate is associated with better outcomes in patients with heart failure (HF) with reduced ejection fraction (EF). Less is known about this association in patients with HF with preserved ejection fraction (HFpEF).ObjectivesThe aims of this study were to examine associations of discharge heart rate with outcomes in hospitalized patients with HFpEF.MethodsOf the 8,873 hospitalized patients with HFpEF (EF ≥50%) in the Medicare-linked OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) registry, 6,286 had a stable heart rate, defined as ≤20 beats/min variation between admission and discharge. Of these, 2,369 (38%) had a discharge heart rate of