학술논문
Long-term clinical outcomes of patients with COVID-19 and chronic liver disease: US multicenter COLD study.
Document Type
article
Author
Aby, Elizabeth S; Moafa, Ghady; Latt, Nyan; Sultan, Mohammad T; Cacioppo, Paula A; Kumar, Sonal; Chung, Raymond T; Bloom, Patricia P; Gustafson, Jenna; Daidone, Michael; Reinus, Zoe; Debes, Jose D; Sandhu, Sunny; Sohal, Aalam; Khalid, Sameeha; Roytman, Marina; Catana, Andreea Maria; Wegermann, Kara; Carr, Rotonya M; Saiman, Yedidya; Kassab, Ihab; Chen, Vincent L; Rabiee, Atoosa; Rosenberg, Carly; Nguyen, Veronica; Gainey, Christina; Zhou, Kali; Chavin, Kenneth; Lizaola-Mayo, Blanca C; Chascsa, David M; Varelas, Lee; Moghe, Akshata; Dhanasekaran, Renumathy
Source
Hepatology communications. 7(1)
Subject
Language
Abstract
BackgroundCOVID-19 is associated with higher morbidity and mortality in patients with chronic liver diseases (CLDs). However, our understanding of the long-term outcomes of COVID-19 in patients with CLD is limited.MethodsWe conducted a multicenter, observational cohort study of adult patients with CLD who were diagnosed with COVID-19 before May 30, 2020, to determine long-term clinical outcomes. We used a control group of patients with CLD confirmed negative for COVID-19.ResultsWe followed 666 patients with CLD (median age 58 years, 52.8% male) for a median of 384 (interquartile range: 31-462) days. The long-term mortality was 8.1%; with 3.6% experiencing delayed COVID-19-related mortality. Compared to a propensity-matched control group of patients with CLD without COVID-19 (n=1332), patients with CLD with COVID-19 had worse long-term survival [p