학술논문
Common Genetic Variation and Age of Onset of Anorexia Nervosa.
Document Type
article
Author
Watson, Hunna J; Thornton, Laura M; Yilmaz, Zeynep; Baker, Jessica H; Coleman, Jonathan RI; Adan, Roger AH; Alfredsson, Lars; Andreassen, Ole A; Ask, Helga; Berrettini, Wade H; Boehnke, Michael; Boehm, Ilka; Boni, Claudette; Buehren, Katharina; Bulant, Josef; Burghardt, Roland; Chang, Xiao; Cichon, Sven; Cone, Roger D; Courtet, Philippe; Crow, Scott; Crowley, James J; Danner, Unna N; de Zwaan, Martina; Dedoussis, George; DeSocio, Janiece E; Dick, Danielle M; Dikeos, Dimitris; Dina, Christian; Djurovic, Srdjan; Dmitrzak-Weglarz, Monika; Docampo-Martinez, Elisa; Duriez, Philibert; Egberts, Karin; Ehrlich, Stefan; Eriksson, Johan G; Escaramís, Geòrgia; Esko, Tõnu; Estivill, Xavier; Farmer, Anne; Fernández-Aranda, Fernando; Fichter, Manfred M; Föcker, Manuel; Foretova, Lenka; Forstner, Andreas J; Frei, Oleksandr; Gallinger, Steven; Giegling, Ina; Giuranna, Johanna; Gonidakis, Fragiskos; Gorwood, Philip; Gratacòs, Mònica; Guillaume, Sébastien; Guo, Yiran; Hakonarson, Hakon; Hauser, Joanna; Havdahl, Alexandra; Hebebrand, Johannes; Helder, Sietske G; Herms, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Hinney, Anke; Hübel, Christopher; Hudson, James I; Imgart, Hartmut; Jamain, Stephanie; Janout, Vladimir; Jiménez-Murcia, Susana; Jones, Ian R; Julià, Antonio; Kalsi, Gursharan; Kaminská, Deborah; Kaprio, Jaakko; Karhunen, Leila; Kas, Martien JH; Keel, Pamela K; Kennedy, James L; Keski-Rahkonen, Anna; Kiezebrink, Kirsty; Klareskog, Lars; Klump, Kelly L; Knudsen, Gun Peggy S; La Via, Maria C; Le Hellard, Stephanie; Leboyer, Marion; Li, Dong; Lilenfeld, Lisa; Lin, Bochao; Lissowska, Jolanta; Luykx, Jurjen; Magistretti, Pierre; Maj, Mario; Marsal, Sara; Marshall, Christian R; Mattingsdal, Morten; Meulenbelt, Ingrid; Micali, Nadia; Mitchell, Karen S; Monteleone, Alessio Maria
Source
Biological psychiatry global open science. 2(4)
Subject
Language
Abstract
BackgroundGenetics and biology may influence the age of onset of anorexia nervosa (AN). The aims of this study were to determine whether common genetic variation contributes to age of onset of AN and to investigate the genetic associations between age of onset of AN and age at menarche.MethodsA secondary analysis of the Psychiatric Genomics Consortium genome-wide association study (GWAS) of AN was performed, which included 9335 cases and 31,981 screened controls, all from European ancestries. We conducted GWASs of age of onset, early-onset AN (