학술논문
18F-fluciclovine PET-CT and 68Ga-PSMA-11 PET-CT in patients with early biochemical recurrence after prostatectomy: a prospective, single-centre, single-arm, comparative imaging trial
Document Type
article
Author
Calais, Jeremie; Ceci, Francesco; Eiber, Matthias; Hope, Thomas A; Hofman, Michael S; Rischpler, Christoph; Bach-Gansmo, Tore; Nanni, Cristina; Savir-Baruch, Bital; Elashoff, David; Grogan, Tristan; Dahlbom, Magnus; Slavik, Roger; Gartmann, Jeannine; Nguyen, Kathleen; Lok, Vincent; Jadvar, Hossein; Kishan, Amar U; Rettig, Matthew B; Reiter, Robert E; Fendler, Wolfgang P; Czernin, Johannes
Source
The Lancet Oncology. 20(9)
Subject
Language
Abstract
BackgroundNational Comprehensive Cancer Network guidelines consider 18F-fluciclovine PET-CT for prostate cancer biochemical recurrence localisation after radical prostatectomy, whereas European Association of Urology guidelines recommend prostate-specific membrane antigen (PSMA) PET-CT. To the best of our knowledge, no prospective head-to-head comparison between these tests has been done so far. The aim of this study was to compare prospectively paired 18F-fluciclovine and PSMA PET-CT scans for localising biochemical recurrence of prostate cancer after radical prostatectomy in patients with low prostate-specific antigen (PSA) concentrations (