학술논문
Impact of Social Vulnerability on Comorbid Cancer and Cardiovascular Disease Mortality in the United States.
Document Type
article
Author
Ganatra, Sarju; Dani, Sourbha S; Kumar, Ashish; Khan, Safi U; Wadhera, Rishi; Neilan, Tomas G; Thavendiranathan, Paaladinesh; Barac, Ana; Hermann, Joerg; Leja, Monika; Deswal, Anita; Fradley, Michael; Liu, Jennifer E; Sadler, Diego; Asnani, Aarti; Baldassarre, Lauren A; Gupta, Dipti; Yang, Eric; Guha, Avirup; Brown, Sherry-Ann; Stevens, Jennifer; Hayek, Salim S; Porter, Charles; Kalra, Ankur; Baron, Suzanne J; Ky, Bonnie; Virani, Salim S; Kazi, Dhruv; Nasir, Khurram; Nohria, Anju
Source
JACC. CardioOncology. 4(3)
Subject
Language
Abstract
Racial and social disparities exist in outcomes related to cancer and cardiovascular disease (CVD).The aim of this cross-sectional study was to study the impact of social vulnerability on mortality attributed to comorbid cancer and CVD.The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database (2015-2019) was used to obtain county-level mortality data attributed to cancer, CVD, and comorbid cancer and CVD. County-level social vulnerability index (SVI) data (2014-2018) were obtained from the CDC's Agency for Toxic Substances and Disease Registry. SVI percentiles were generated for each county and aggregated to form SVI quartiles. Age-adjusted mortality rates (AAMRs) were estimated and compared across SVI quartiles to assess the impact of social vulnerability on mortality related to cancer, CVD, and comorbid cancer and CVD.The AAMR for comorbid cancer and CVD was 47.75 (95% CI: 47.66-47.85) per 100,000 person-years, with higher mortality in counties with greater social vulnerability. AAMRs for cancer and CVD were also significantly greater in counties with the highest SVIs. However, the proportional increase in mortality between the highest and lowest SVI counties was greater for comorbid cancer and CVD than for either cancer or CVD alone. Adults