학술논문
The effect of time since stroke, gender, age, and lesion size on thalamus volume in chronic stroke: a pilot study
Document Type
article
Author
Krishnamurthy, Lisa C; Champion, Gabriell N; McGregor, Keith M; Krishnamurthy, Venkatagiri; Turabi, Aaminah; Roberts, Simone R; Nocera, Joe R; Borich, Michael R; Rodriguez, Amy D; Belagaje, Samir R; Harrington, Rachael M; Harris-Love, Michelle L; Harnish, Stacy M; Drucker, Jonathan H; Benjamin, Michelle; Meadows, M Lawson; Seeds, Lauren; Zlatar, Zvinka Z; Sudhyadhom, Atchar; Butler, Andrew J; Garcia, Amanda; Patten, Carolynn; Trinastic, Jonathan; Kautz, Steven A; Gregory, Chris; Crosson, Bruce A
Source
Scientific Reports. 10(1)
Subject
Language
Abstract
Recent stroke studies have shown that the ipsi-lesional thalamus longitudinally and significantly decreases after stroke in the acute and subacute stages. However, additional considerations in the chronic stages of stroke require exploration including time since stroke, gender, intracortical volume, aging, and lesion volume to better characterize thalamic differences after cortical infarct. This cross-sectional retrospective study quantified the ipsilesional and contralesional thalamus volume from 69 chronic stroke subjects' anatomical MRI data (age 35-92) and related the thalamus volume to time since stroke, gender, intracortical volume, age, and lesion volume. The ipsi-lesional thalamus volume was significantly smaller than the contra-lesional thalamus volume (t(68) = 13.89, p