학술논문

Can increased visceral adiposity without body weight changes accelerate carotid atherosclerosis in South Korean participants with type 2 diabetes?
Document Type
article
Source
Journal of Diabetes and its Complications. 29(8)
Subject
Biomedical and Clinical Sciences
Nutrition and Dietetics
Cardiovascular
Clinical Research
Diabetes
Atherosclerosis
Obesity
Nutrition
Metabolic and endocrine
Cancer
Adiposity
Aged
Body Mass Index
Carotid Artery Diseases
Carotid Intima-Media Thickness
Cohort Studies
Diabetes Mellitus
Type 2
Diabetic Angiopathies
Disease Progression
Female
Hospitals
Special
Hospitals
Urban
Humans
Insulin Resistance
Intra-Abdominal Fat
Male
Middle Aged
Obesity
Abdominal
Prevalence
Republic of Korea
Risk Factors
Waist Circumference
Carotid atherosclerosis
Carotid intima-media thickness
Type 2 diabetes mellitus
Visceral fat thickness
Clinical Sciences
Endocrinology & Metabolism
Clinical sciences
Language
Abstract
AimsType 2 diabetes mellitus (T2DM) and visceral obesity are associated with each other and with cardiovascular diseases. We determined whether increased visceral adiposity without weight gain was associated with sex-specific accelerated carotid atherosclerosis in South Koreans with T2DM.MethodsFrom 2003 to 2012, we recruited 280 participants with T2DM for the Seoul Metabolic Syndrome cohort who had body weight, visceral fat thickness (VFT), and carotid intima-media thickness (CIMT) measured at intervals of 2years. According to VFT change, sex-specific quartiles of clinical characteristics and changes of CIMT were determined. Logistic regression models predicted the odds of the progression of CIMTs in each quartile.ResultsDuring 2years of observation, VFTs fell by 5.2±13.5mm in men (P