학술논문

The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods
Document Type
article
Source
Pain Medicine. 24(Suppl 1)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Health Sciences
Substance Misuse
Neurosciences
Clinical Research
Pain Research
Chronic Pain
Drug Abuse (NIDA only)
Good Health and Well Being
Adult
Humans
Research Design
Analgesics
Opioid
Advisory Committees
Pain Measurement
Low Back Pain
Opioid-Related Disorders
Chronic low back pain
BACPAC Research Consortium
Harmonization
Back Pain
HEAL
SMART
clinical trials
chronic disease
chronic pain
low back pain
Pharmacology and Pharmaceutical Sciences
Public Health and Health Services
Anesthesiology
Clinical sciences
Health services and systems
Clinical and health psychology
Language
Abstract
In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, treatable cause for back pain is challenging, especially as it is often attributed to complex, multifaceted issues involving biological, psychological, and social components. Due to the difficulty in treating the true cause of chronic low back pain (cLBP), an over-reliance on opioid pain medications among cLBP patients has developed, which is associated with increased prevalence of opioid use disorder and increased risk of death. To combat the rise of opioid-related deaths, the National Institutes of Health (NIH) initiated the Helping to End Addiction Long-TermSM (HEAL) initiative, whose goal is to address the causes and treatment of opioid use disorder while also seeking to better understand, diagnose, and treat chronic pain. The NIH Back Pain Consortium (BACPAC) Research Program, a network of 14 funded entities, was launched as a part of the HEAL initiative to help address limitations surrounding the diagnosis and treatment of cLBP. This paper provides an overview of the BACPAC research program's goals and overall structure, and describes the harmonization efforts across the consortium, define its research agenda, and develop a collaborative project which utilizes the strengths of the network. The purpose of this paper is to serve as a blueprint for other consortia tasked with the advancement of pain related science.