학술논문

Neurological complications associated with emerging viruses in Brazil
Document Type
article
Source
International Journal of Gynecology & Obstetrics. 148(Suppl 2)
Subject
Medical Microbiology
Biomedical and Clinical Sciences
Clinical Sciences
Infectious Diseases
Biodefense
Rare Diseases
Neurosciences
Prevention
Vaccine Related
Peripheral Neuropathy
Emerging Infectious Diseases
Influenza
Infection
Good Health and Well Being
Adult
Autoimmune Diseases of the Nervous System
Brazil
Cross-Sectional Studies
Epidemiological Monitoring
Female
Guillain-Barre Syndrome
Hospitalization
Humans
Incidence
Male
Middle Aged
Zika Virus
Zika Virus Infection
Arboviruses
Guillain-Barre syndrome
Human influenza
Peripheral nervous system diseases
Polyneuropathies
Public hospitals
Sentinel surveillance
Guillain-Barré syndrome
Paediatrics and Reproductive Medicine
Obstetrics & Reproductive Medicine
Reproductive medicine
Language
Abstract
OBJECTIVE:To test the hypotheses that emerging viruses are associated with neurological hospitalizations and that statistical models can be used to predict neurological sequelae from viral infections. METHODS:An ecological study was carried out to observe time trends in the number of hospitalizations with inflammatory polyneuropathy and Guillain-Barré syndrome (GBS) in the state of Rio de Janeiro from 1997 to 2017. Increases in GBS from month to month were assessed using a Farrington test. In addition, a cross-sectional study was conducted analyzing 50 adults hospitalized for inflammatory polyneuropathies from 2015 to 2017. The extent to which Zika virus symptoms explained GBS hospitalizations was evaluated using a calibration test. RESULTS:There were significant increases (Farrington test, P