학술논문

Accurate phase retrieval of complex 3D point spread functions with deep residual neural networks
Document Type
article
Source
Applied Physics Letters. 115(25)
Subject
Physical Sciences
Neurosciences
Engineering
Technology
Applied Physics
Physical sciences
Language
Abstract
Phase retrieval, i.e., the reconstruction of phase information from intensity information, is a central problem in many optical systems. Imaging the emission from a point source such as a single molecule is one example. Here, we demonstrate that a deep residual neural net is able to quickly and accurately extract the hidden phase for general point spread functions (PSFs) formed by Zernike-type phase modulations. Five slices of the 3D PSF at different focal positions within a two micrometer range around the focus are sufficient to retrieve the first six orders of Zernike coefficients.