학술논문

Endovascular Management of Distal ACA Aneurysms: Single-Institution Clinical Experience in 22 Consecutive Patients and Literature Review
Document Type
article
Source
American Journal of Neuroradiology. 34(8)
Subject
Biomedical and Clinical Sciences
Ophthalmology and Optometry
Brain Disorders
Neurosciences
Stroke
Cardiovascular
Clinical Research
Adult
Aged
Aged
80 and over
Cerebral Angiography
Cerebral Revascularization
Endovascular Procedures
Female
Humans
Intracranial Aneurysm
Male
Middle Aged
Retrospective Studies
Treatment Outcome
Clinical Sciences
Nuclear Medicine & Medical Imaging
Clinical sciences
Physical chemistry
Language
Abstract
Background and purposeDistal ACA aneurysms remain difficult to treat with endovascular therapy, but improved technology and experience allows for the treatment of some of these aneurysms with excellent results. The purpose of this study was to assess the status of endovascular treatment of distal ACA aneurysms by comparing our results with recent endovascular and microsurgical series of distal ACA aneurysms.Materials and methodsBetween 2000 and 2008, a total of 22 consecutive patients (14 women; mean age, 58.4 years) with distal ACA aneurysms underwent coil placement at Barrow Neurological Institute. Clinical presentations, radiographic findings, endovascular management, and outcomes were reviewed retrospectively.ResultsOf the 22 patients, 13 (59%) presented with subarachnoid hemorrhage. Six patients were HH grade I or II, 1 was grade III, 5 were grade IV, and 1 was grade V. Frontal lobe hematomas occurred in 5 patients with ruptured aneurysms. The mean aneurysm size was 7.5 mm (range, 2.8-25 mm); 55% were smaller than 7 mm. Twelve aneurysms (55%) arose from the origin of the callosomarginal artery (55%). Complete occlusion was achieved in 50% of the cases and near-complete occlusion in 45%. The few periprocedural complications included 1 retroperitoneal hematoma and 1 intraoperative rupture. Four patients had thromboembolic events adequately treated intraprocedurally with abciximab. No deaths occurred in the patients treated.ConclusionsThe characteristics of the patients and aneurysms treated in our series were comparable to previous reports of endovascular treatment of ACA aneurysms with respect to rupture status. Periprocedural morbidity and mortality rates in our series fared well compared with previous reports, as did our combined rate of complete or near-complete occlusions. Recent advances in endovascular devices and techniques have improved outcomes of distal ACA aneurysms.