학술논문

Silent hypoxaemia in COVID-19 patients.
Document Type
article
Source
The Journal of physiology. 599(4)
Subject
Humans
Dyspnea
Hypoxia
COVID-19
SARS-CoV-2
dyspnoea
happy hypoxia
silent hypoxaemia
Biological Sciences
Medical and Health Sciences
Physiology
Language
Abstract
The clinical presentation of COVID-19 due to infection with SARS-CoV-2 is highly variable with the majority of patients having mild symptoms while others develop severe respiratory failure. The reason for this variability is unclear but is in critical need of investigation. Some COVID-19 patients have been labelled with 'happy hypoxia', in which patient complaints of dyspnoea and observable signs of respiratory distress are reported to be absent. Based on ongoing debate, we highlight key respiratory and neurological components that could underlie variation in the presentation of silent hypoxaemia and define priorities for subsequent investigation.