학술논문
Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
Document Type
article
Author
Hemmelder, Marc H; Noordzij, Marlies; Vart, Priya; Hilbrands, Luuk B; Jager, Kitty J; Abrahams, Alferso C; Arroyo, David; Battaglia, Yuri; Ekart, Robert; Mallamaci, Francesca; Malloney, Sharon-Rose; Oliveira, Joao; Rydzewski, Andrzej; Sridharan, Sivakumar; Vogt, Liffert; Duivenvoorden, Raphaël; Gansevoort, Ron T; Franssen, Casper FM; van der Net, Jeroen B; Essig, Marie; du Buf-Vereijken, Peggy WG; van Ginneken, Betty; Maas, Nanda; van Jaarsveld, Brigit C; Bemelman, Frederike J; Klingenberg-Salahova, Farah; Heenan-Vos, Frederiek; Vervloet, Marc G; Nurmohamed, Azam; Abramowicz, Daniel; Verhofstede, Sabine; Maoujoud, Omar; Malfait, Thomas; Fialova, Jana; Melilli, Edoardo; Favà, Alexandre; Cruzado, Josep M; Perez, Nuria Montero; Lips, Joy; Krepel, Harmen; Adilovic, Harun; Hengst, Maaike; Konings, Constantijn JAM; Braconnier, Philippe; Weis, Daniel; Gellert, Ryszard; Alferes, Daniela G; Radulescu, Daniela; Zakharova, Elena V; Ambuehl, Patrice Max; Guidotti, Rebecca; Walker, Andrea; Lepeytre, Fanny; Rabaté, Clémentine; Rostoker, Guy; Marques, Sofia; Azasevac, Tijana; Majstorovic, Gordana Strazmester; Katicic, Dajana; Dam, Marc ten; Krüger, Thilo; Brzosko, Szymon; Liakopoulos, Vassilios; Zanen, Adriaan L; Logtenberg, Susan JJ; Fricke, Lutz; Kuryata, Olexandr; Slebe, Jeroen JP; ElHafeez, Samar Abd; Kemlin, Delphine; van de Wetering, Jacqueline; Reinders, Marlies EJ; Hesselink, Dennis A; van Gestel, J Kal-; Eiselt, Jaromir; Kielberger, Lukas; El-Wakil, Hala S; Verhoeven, Martine AM; Logan, Ian; Canal, Cristina; Facundo, Carme; Ramos, Ana M; Debska-Slizien, Alicja; Veldhuizen, Nicoline MH; Tigka, Eirini; Konsta, Maria Anna Polyzou; Panagoutsos, Stylianos; Postorino, Adele; Cambareri, Francesco; Matceac, Irina; Nistor, Ionut; Covic, Adrian; Groeneveld, JHM; Jousma, Jolanda; van Buren, Marjolijn; Diekmann, Fritz; Oppenheimer, Federico; Blasco, Miquel; Pereira, Tiago Assis; dos Santos, Augusto Cesar Soares
Source
Nephrology Dialysis Transplantation. 37(6)
Subject
Language
Abstract
BackgroundCoronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis.MethodsWe analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression.ResultsIn 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8-6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome.ConclusionsMortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.