학술논문

International Consensus Statement on Obstructive Sleep Apnea
Document Type
article
Author
Chang, Jolie LGoldberg, Andrew NAlt, Jeremiah AMohammed, AlzoubaidiAshbrook, LizaAuckley, DennisAyappa, InduBakhtiar, HiraBarrera, José EBartley, Bethany LBillings, Martha EBoon, Maurits SBosschieter, PienBraverman, ItzhakBrodie, KaraCabrera‐Muffly, CristinaCaesar, RayCahali, Michel BCai, YiCao, MichelleCapasso, RobsonCaples, Sean MChahine, Lana MChang, Corissa PChang, Katherine WChaudhary, NilikaCheong, Crystal SJChowdhuri, SusmitaCistulli, Peter AClaman, DavidCollen, JacobCoughlin, Kevin CCreamer, JenniferDavis, Eric MDupuy‐McCauley, Kara LDurr, Megan LDutt, MohanAli, Mazen ElElkassabany, Nabil MEpstein, Lawrence JFiala, Justin AFreedman, NeilGill, KiratGillespie, M BoydGolisch, LeaGooneratne, NalakaGottlieb, Daniel JGreen, Katherine KGulati, ArushiGurubhagavatula, IndiraHayward, NathanHoff, Paul THoffmann, Oliver MGHolfinger, Steven JHsia, JenniferHuntley, ColinHuoh, Kevin CHuyett, PhillipInala, SanjanaIshman, Stacey LJella, Tarun KJobanputra, Aesha MJohnson, Andrew PJunna, Mithri RKado, Jenna TKaffenberger, Thomas MKapur, Vishesh KKezirian, Eric JKhan, MeenaKirsch, Douglas BKominsky, AlanKryger, MeirKrystal, Andrew DKushida, Clete AKuzniar, Thomas JLam, Derek JLettieri, Christopher JLim, Diane CLin, Hsin‐ChingLiu, Stanley YCMacKay, Stuart GMagalang, Ulysses JMalhotra, AtulMansukhani, Meghna PMaurer, Joachim TMay, Anna MMitchell, Ron BMokhlesi, BabakMullins, Anna ENada, Eman MNaik, SreelathaNokes, BrandonOlson, Michael DPack, Allan IPang, Edward BPang, Kenny PPatil, Susheel PVan de Perck, EliPiccirillo, Jay FPien, Grace W
Source
International Forum of Allergy & Rhinology. 13(7)
Subject
Biomedical and Clinical Sciences
Cardiovascular Medicine and Haematology
Health Services
Lung
Sleep Research
Clinical Research
Prevention
Respiratory
Good Health and Well Being
Adult
Humans
Sleep Apnea
Obstructive
Continuous Positive Airway Pressure
Polysomnography
Risk Factors
atrial fibrillation
cardiovascular event
cerebrovascular disease
consensus
dementia
evidence-based medicine
home sleep apnea testing
hypertension
hypoglossal nerve stimulation
mortality
motor vehicle accidents
neurocognitive function
obstructive sleep apnea
outcomes
PAP adherence
perioperative management
polysomnography
positive airway pressure
screening
sleep
sleep disordered breathing
sleepiness
sleep surgery
surgical outcomes
systematic review
treatment outcomes
uvulopalatopharyngoplasty
Immunology
Clinical sciences
Language
Abstract
BackgroundEvaluation and interpretation of the literature on obstructive sleep apnea (OSA) allows for consolidation and determination of the key factors important for clinical management of the adult OSA patient. Toward this goal, an international collaborative of multidisciplinary experts in sleep apnea evaluation and treatment have produced the International Consensus statement on Obstructive Sleep Apnea (ICS:OSA).MethodsUsing previously defined methodology, focal topics in OSA were assigned as literature review (LR), evidence-based review (EBR), or evidence-based review with recommendations (EBR-R) formats. Each topic incorporated the available and relevant evidence which was summarized and graded on study quality. Each topic and section underwent iterative review and the ICS:OSA was created and reviewed by all authors for consensus.ResultsThe ICS:OSA addresses OSA syndrome definitions, pathophysiology, epidemiology, risk factors for disease, screening methods, diagnostic testing types, multiple treatment modalities, and effects of OSA treatment on multiple OSA-associated comorbidities. Specific focus on outcomes with positive airway pressure (PAP) and surgical treatments were evaluated.ConclusionThis review of the literature consolidates the available knowledge and identifies the limitations of the current evidence on OSA. This effort aims to create a resource for OSA evidence-based practice and identify future research needs. Knowledge gaps and research opportunities include improving the metrics of OSA disease, determining the optimal OSA screening paradigms, developing strategies for PAP adherence and longitudinal care, enhancing selection of PAP alternatives and surgery, understanding health risk outcomes, and translating evidence into individualized approaches to therapy.