학술논문
Detection and Characterization of Enterovirus B73 from a Child in Brazil
Document Type
article
Author
de Oliveira Ribeiro, Geovani; Luchs, Adriana; de Pádua Milagres, Flávio Augusto; Komninakis, Shirley Vasconcelos; Gill, Danielle Elise; Lobato, Márcia Cristina Alves Brito Sayão; Brustulin, Rafael; Chagas, Rogério Togisaki das; dos Santos Abrão, Maria de Fátima Neves; de Deus Alves Soares, Cassia Vitória; Witkin, Steven S; Villanova, Fabiola; Deng, Xutao; Sabino, Ester Cerdeira; Delwart, Eric; da Costa, Antonio Charlys; Leal, Élcio
Source
Viruses. 11(1)
Subject
Language
Abstract
Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a child with acute gastroenteritis living in a rural area in Northern Brazil. The subject was not infected with any known enteric pathogens such as norovirus, rotavirus, helminths, or enteric bacteria. Analysis of the nearly full-length TO-127 genome (6993 nt) indicated a 74⁻75% nucleotide similarity with EV-B73 strains from other countries. Evolutionary analysis suggests that B73 is endemic and widespread.