학술논문

COVID‐19 pandemic and impact on cancer clinical trials: An academic medical center perspective
Document Type
article
Source
Cancer Medicine. 9(17)
Subject
Biomedical and Clinical Sciences
Oncology and Carcinogenesis
Clinical Research
Cancer
Patient Safety
Health Services
Good Health and Well Being
Academic Medical Centers
Ambulatory Care
COVID-19
Clinical Trials as Topic
Health Personnel
Humans
Neoplasms
Risk Factors
Telemedicine
Translational Research
Biomedical
cancer
clinical trials
oncology
pandemic
Biochemistry and Cell Biology
Oncology and carcinogenesis
Language
Abstract
The COVID-19 pandemic changed health-care operations around the world and has interrupted standard clinical practices as well as created clinical research challenges for cancer patients. Cancer patients are uniquely susceptible to COVID-19 infection and have some of the worst outcomes. Importantly, cancer therapeutics could potentially render cancer patients more susceptible to demise from COVID-19 yet the poor survival outcome of many cancer diagnoses outweighs this risk. In addition, the pandemic has resulted in risks to health-care workers and research staff driving important change in clinical research operations and procedures. Remote telephone and video visits, remote monitoring, electronic capture of signatures and data, and limiting sample collections have allowed the leadership in our institution to ensure the safety of our staff and patients while continuing critical clinical research operations. Here we discuss some of these unique challenges and our response to change that was necessary to continue cancer clinical research; and, the impacts the pandemic has caused including increases in efficiency for our cancer research office.