학술논문

The Toxicology Investigators Consortium Case Registry-the 2019 Annual Report.
Document Type
article
Source
Journal of medical toxicology : official journal of the American College of Medical Toxicology. 16(4)
Subject
Toxicology Investigators Consortium Study Group
Humans
Poisoning
Prognosis
Registries
Suicide
Toxicology
Time Factors
Databases
Factual
Adolescent
Adult
Aged
Aged
80 and over
Middle Aged
Child
Child
Preschool
Infant
Female
Male
Young Adult
Drug Overdose
Epidemiology
Medical toxicology
Overdose
Surveillance
Substance Misuse
Pain Research
Brain Disorders
Drug Abuse (NIDA only)
Behavioral and Social Science
Neurosciences
Good Health and Well Being
Clinical Sciences
Pharmacology and Pharmaceutical Sciences
Language
Abstract
The Toxicology Investigators Consortium (ToxIC) Registry was established by the American College of Medical Toxicology (ACMT) in 2010. The Registry collects data from participating sites with the agreement that all bedside medical toxicology consultation will be entered. This tenth annual report summarizes the Registry's 2019 data and activity with its additional 7177 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from 1 January to 31 December 2019. Detailed data was collected from these cases and aggregated to provide information which included demographics, reason for medical toxicology evaluation, agent and agent class, clinical signs and symptoms, treatments and antidotes administered, mortality, and whether life support was withdrawn. 50.7% of cases were female, 48.5% were male, and 0.8% were transgender. Non-opioid analgesics was the most commonly reported agent class, followed by opioid and antidepressant classes. Acetaminophen was once again the most common agent reported. There were 91 fatalities, comprising 1.3% of all Registry cases. Major trends in demographics and exposure characteristics remained similar to past years' reports. Sub-analyses were conducted to describe exposures in cases of self-harm, gender differences in substance use disorder, and trends in addiction medicine and pain management consultations.