학술논문
Butler enables rapid cloud-based analysis of thousands of human genomes
Document Type
article
Source
Nature Biotechnology. 38(3)
Subject
Language
Abstract
We present Butler, a computational tool that facilitates large-scale genomic analyses on public and academic clouds. Butler includes innovative anomaly detection and self-healing functions that improve the efficiency of data processing and analysis by 43% compared with current approaches. Butler enabled processing of a 725-terabyte cancer genome dataset from the Pan-Cancer Analysis of Whole Genomes (PCAWG) project in a time-efficient and uniform manner.