학술논문

Using a chat-based informed consent tool in large-scale genomic research.
Document Type
article
Source
Journal of the American Medical Informatics Association. 31(2)
Subject
chatbot
genetic counseling
genomics
informed consent
large-scale research
Humans
Prospective Studies
Informed Consent
Genomics
Software
Communication
Language
Abstract
OBJECTIVE: We implemented a chatbot consent tool to shift the time burden from study staff in support of a national genomics research study. MATERIALS AND METHODS: We created an Institutional Review Board-approved script for automated chat-based consent. We compared data from prospective participants who used the tool or had traditional consent conversations with study staff. RESULTS: Chat-based consent, completed on a users schedule, was shorter than the traditional conversation. This did not lead to a significant change in affirmative consents. Within affirmative consents and declines, more prospective participants completed the chat-based process. A quiz to assess chat-based consent user understanding had a high pass rate with no reported negative experiences. CONCLUSION: Our report shows that a structured script can convey important information while realizing the benefits of automation and burden shifting. Analysis suggests that it may be advantageous to use chatbots to scale this rate-limiting step in large research projects.