학술논문

Light‐based treatment of pediatric port‐wine birthmarks
Document Type
article
Source
Pediatric Dermatology. 38(2)
Subject
Pediatric
Clinical Research
Adult
Child
Cohort Studies
Humans
Lasers
Dye
Low-Level Light Therapy
Port-Wine Stain
Treatment Outcome
developmental defects
genetic diseases
mechanisms
laser
vascular malformation
genetic diseases/mechanisms
Paediatrics and Reproductive Medicine
Dermatology & Venereal Diseases
Language
Abstract
Port-wine birthmarks (PWBs) are progressive vascular malformations with significant disfigurement and psychosocial morbidity; early light-based treatment has shown improved outcomes in the pediatric population. Somatic mosaic mutations underly the progressive nature of PWBs and explain the significant differences in response and heterogeneity of vessel architecture in the pediatric population when compared to the adult cohort. Here, we summarize a review of pediatric specific literature on the various light-based treatment modalities, including pulsed dye laser, near-infrared lasers, and intense pulsed light, providing the various indications, tips, advantages, and disadvantages for the pediatric dermatologist.