학술논문

Inpatient Point-of-Care HIV Early Infant Diagnosis in Mozambique to Improve Case Identification and Linkage to Antiretroviral Therapy
Document Type
article
Source
Global Health Science and Practice. 9(1)
Subject
Health Services and Systems
Public Health
Health Sciences
Pediatric
Prevention
Infectious Diseases
Patient Safety
Clinical Research
HIV/AIDS
Health Services
Good Health and Well Being
Child
Female
HIV Infections
Humans
Infant
Infectious Disease Transmission
Vertical
Inpatients
Mozambique
Point-of-Care Systems
Retrospective Studies
Health services and systems
Public health
Language
Abstract
IntroductionNovel approaches to case identification and linkage to antiretroviral therapy (ART) are needed to close gaps in early infant diagnosis (EID) of HIV. Point-of-care (POC) EID is a recent innovation that eliminates the long turnaround times of conventional EID that limit patient management in the inpatient setting. The initial deployment of POC EID in Mozambique focused primarily on outpatient clinics; however, 2 high-volume tier-4 pediatric referral hospitals were also included.MethodsTo assess the impact of inpatient POC EID, a retrospective review of testing and care data from Hospital Central de Beira (HCB) and Hospital Central de Maputo (HCM) was performed for the period September 2017 to July 2018, with comparison to the 8-month pre-POC period when dried blood spots were used for conventional EID.ResultsMonthly testing volume increased from 8.5 tests pre-POC to 17.6 tests with POC (P