학술논문

Association of Hepatic Steatosis with Adipose and Muscle Mass and Distribution in Children
Document Type
article
Source
Metabolic Syndrome and Related Disorders. 21(4)
Subject
Biomedical and Clinical Sciences
Nutrition and Dietetics
Pediatric
Digestive Diseases
Biomedical Imaging
Nutrition
Liver Disease
Obesity
Chronic Liver Disease and Cirrhosis
Oral and gastrointestinal
Metabolic and endocrine
Humans
Child
Adiposity
Fatty Liver
Liver
Intra-Abdominal Fat
Magnetic Resonance Imaging
Obesity
Abdominal
Muscles
hepatic steatosis
MRI-PDFF
adipose
muscle
nonalcoholic fatty liver disease
Medical Biotechnology
Clinical Sciences
Public Health and Health Services
Endocrinology & Metabolism
Medical biotechnology
Public health
Language
Abstract
Background: Pediatric studies have shown associations between hepatic steatosis and total body fat, visceral fat, and lean mass. However, these associations have not been assessed simultaneously, leaving their relative importance unknown. Objective: To evaluate associations between hepatic steatosis and total-body adiposity, visceral adiposity, and lean mass in children. Method: In children at risk for fatty liver, hepatic steatosis, adipose, and lean mass were estimated with magnetic resonance imaging and dual-energy X-ray absorptiometry. Results: Two hundred twenty-seven children with mean age 12.1 years had mean percent body fat of 38.9% and mean liver fat of 8.4%. Liver fat was positively associated with total-body adiposity, visceral adiposity, and lean mass (P