학술논문
Higher Risks of Toxicity and Incomplete Recovery in 13- to 17-Year-Old Females after Marrow Donation: RDSafe Peds Results.
Document Type
article
Author
Pulsipher, Michael A; Logan, Brent R; Kiefer, Deidre M; Chitphakdithai, Pintip; Riches, Marcie L; Rizzo, J Douglas; Anderlini, Paolo; Leitman, Susan F; Varni, James W; Kobusingye, Hati; Besser, RaeAnne M; Miller, John P; Drexler, Rebecca J; Abdel-Mageed, Aly; Ahmed, Ibrahim A; Ball, Edward D; Bolwell, Brian J; Bunin, Nancy J; Cheerva, Alexandra; Delgado, David C; Dvorak, Christopher C; Gillio, Alfred P; Hahn, Theresa E; Hale, Gregory A; Haight, Ann E; Hayes-Lattin, Brandon M; Kasow, Kimberly A; Linenberger, Michael; Magalhaes-Silverman, Margarida; Mori, Shahram; Prasad, Vinod K; Quigg, Troy C; Sahdev, Indira; Schriber, Jeffrey R; Shenoy, Shalini; Tse, William T; Yanik, Gregory A; Navarro, Willis H; Horowitz, Mary M; Confer, Dennis L; Shaw, Bronwen E; Switzer, Galen E
Source
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 25(5)
Subject
Language
Abstract
Although donation of bone marrow (BM) or peripheral blood stem cells (PBSCs) from children to family members undergoing allogeneic transplantation are well-established procedures, studies detailing levels of pain, symptoms, and long-term recovery are lacking. To address this lack, we prospectively enrolled 294 donors age 20% of females and males age 13 to 17 years do not return to baseline pain levels by 1 year after BM donation. Studies aimed at decreasing symptoms and improving recovery in older children are warranted.