학술논문

Snapshots: Chromatin control of viral infection
Document Type
article
Source
Virology. 435(1)
Subject
Medical Microbiology
Biomedical and Clinical Sciences
Biological Sciences
Infectious Diseases
Aetiology
2.2 Factors relating to the physical environment
Infection
Chromatin
Chromatin Assembly and Disassembly
DNA Viruses
Epigenesis
Genetic
Gene Expression Regulation
Viral
Genome
Viral
Host-Pathogen Interactions
Humans
RNA Viruses
Virus Diseases
Virus Latency
Virus Replication
Virus
Herpesvirus
Adenovirus
Papillomavirus
Human Immunodeficiency Virus
Influenza virus
Agricultural and Veterinary Sciences
Medical and Health Sciences
Virology
Agricultural
veterinary and food sciences
Biological sciences
Biomedical and clinical sciences
Language
Abstract
Like their cellular host counterparts, many invading viral pathogens must contend with, modulate, and utilize the host cell's chromatin machinery to promote efficient lytic infection or control persistent-latent states. While not intended to be comprehensive, this review represents a compilation of conceptual snapshots of the dynamic interplay of viruses with the chromatin environment. Contributions focus on chromatin dynamics during infection, viral circumvention of cellular chromatin repression, chromatin organization of large DNA viruses, tethering and persistence, viral interactions with cellular chromatin modulation machinery, and control of viral latency-reactivation cycles.