학술논문
Real-World Preliminary Experience With Responsive Neurostimulation in Pediatric Epilepsy: A Multicenter Retrospective Observational Study
Document Type
article
Author
Nagahama, Yasunori; Zervos, Thomas M; Murata, Kristina K; Holman, Lynette; Karsonovich, Torin; Parker, Jonathon J; Chen, Jia-Shu; Phillips, H Westley; Fajardo, Marytery; Nariai, Hiroki; Hussain, Shaun A; Porter, Brenda E; Grant, Gerald A; Ragheb, John; Wang, Shelly; O’Neill, Brent R; Alexander, Allyson L; Bollo, Robert J; Fallah, Aria
Source
Neurosurgery. 89(6)
Subject
Language
Abstract
BackgroundDespite the well-documented utility of responsive neurostimulation (RNS, NeuroPace) in adult epilepsy patients, literature on the use of RNS in children is limited.ObjectiveTo determine the real-world efficacy and safety of RNS in pediatric epilepsy patients.MethodsPatients with childhood-onset drug-resistant epilepsy treated with RNS were retrospectively identified at 5 pediatric centers. Reduction of disabling seizures and complications were evaluated for children (18 yr) and compared with prior literature pertaining to adult patients.ResultsOf 35 patients identified, 17 were