학술논문
Tuning conformation and properties of peptidomimetic backbones through dual N / C α -substitution
Document Type
article
Author
Source
Chemical Communications. 54(41)
Subject
Language
Abstract
We demonstrate that changing the backbone between peptides, peptoids and the underexplored dual N/Cα-substituted peptoids analogues allows for control over the preferred conformation of the intrinsically disordered biomimetic oligomers. The conformation tunability is directly probed using electron paramagnetic resonance (EPR), and is shown to manifest itself in differences in the nanoparticle-oligomer hybridization propensity.