학술논문
Sequentially addressable dielectrophoretic array for high-throughput sorting of large-volume biological compartments.
Document Type
article
Author
Isozaki, A; Nakagawa, Y; Loo, MH; Shibata, Y; Tanaka, N; Setyaningrum, DL; Park, J-W; Shirasaki, Y; Mikami, H; Huang, D; Tsoi, H; Riche, CT; Ota, T; Miwa, H; Kanda, Y; Ito, T; Yamada, K; Iwata, O; Suzuki, K; Ohnuki, S; Ohya, Y; Kato, Y; Hasunuma, T; Matsusaka, S; Yamagishi, M; Yazawa, M; Uemura, S; Nagasawa, K; Watarai, H; Di Carlo, D; Goda, K
Source
Science advances. 6(22)
Subject
Language
Abstract
Droplet microfluidics has become a powerful tool in precision medicine, green biotechnology, and cell therapy for single-cell analysis and selection by virtue of its ability to effectively confine cells. However, there remains a fundamental trade-off between droplet volume and sorting throughput, limiting the advantages of droplet microfluidics to small droplets (