학술논문

Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0©.
Document Type
article
Source
Neurogastroenterology & Motility. 33(1)
Subject
achalasia
esophageal spasm
integrated relaxation pressure
lower esophageal sphincter
peroral endoscopic myotomy
Esophageal Achalasia
Esophageal Motility Disorders
Esophageal Spasm
Diffuse
Esophagogastric Junction
Humans
Manometry
Language
Abstract
Chicago Classification v4.0 (CCv4.0) is the updated classification scheme for esophageal motility disorders using metrics from high-resolution manometry (HRM). Fifty-two diverse international experts separated into seven working subgroups utilized formal validated methodologies over two-years to develop CCv4.0. Key updates in CCv.4.0 consist of a more rigorous and expansive HRM protocol that incorporates supine and upright test positions as well as provocative testing, a refined definition of esophagogastric junction (EGJ) outflow obstruction (EGJOO), more stringent diagnostic criteria for ineffective esophageal motility and description of baseline EGJ metrics. Further, the CCv4.0 sought to define motility disorder diagnoses as conclusive and inconclusive based on associated symptoms, and findings on provocative testing as well as supportive testing with barium esophagram with tablet and/or functional lumen imaging probe. These changes attempt to minimize ambiguity in prior iterations of Chicago Classification and provide more standardized and rigorous criteria for patterns of disorders of peristalsis and obstruction at the EGJ.