학술논문

Differences between patients with type 1 diabetes with optimal and suboptimal glycaemic control: A real‐world study of more than 30 000 patients in a US electronic health record database
Document Type
article
Source
Diabetes Obesity and Metabolism. 22(4)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Clinical Research
Patient Safety
Autoimmune Disease
Health Services
Diabetes
Hypertension
Obesity
Cardiovascular
Heart Disease
Prevention
Metabolic and endocrine
Good Health and Well Being
Adult
Blood Glucose
Diabetes Mellitus
Type 1
Electronic Health Records
Glycated Hemoglobin
Humans
Hypoglycemia
Hypoglycemic Agents
United States
type 1 diabetes
observational study
diabetes complications
database research
cardiovascular disease
diabetes complications
database research
cardiovascular disease
Endocrinology & Metabolism
Clinical sciences
Language
Abstract
AimsTo use electronic health record data from real-world clinical practice to assess demographics, clinical characteristics and disease burden of adults with type 1 diabetes (T1D) in the United States.Materials and methodsRetrospective observational study of adults with T1D for ≥24 months at their first visit with a T1D diagnosis code ("index date") between July 2014 and June 2016 in the Optum Humedica database. Demographic characteristics, acute complications (severe hypoglycaemia [SH], diabetic ketoacidosis [DKA]), microvascular complications, cardiovascular (CV) events and health care resource utilization during the 12 months before the index date ("baseline period") were compared between patients with optimal versus suboptimal glycaemic control (glycated haemoglobin [HbA1c] 30 000 adults with T1D showed that individuals with suboptimal versus optimal glycaemic control differed significantly in terms of health care coverage, comorbidities, diabetes-related complications, health care utilization and CV risk factors. However, suboptimal control was not associated with increased risk of CV outcomes.