학술논문

Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study
Document Type
article
Source
Journal of the American Heart Association. 9(21)
Subject
Pediatric
Perinatal Period - Conditions Originating in Perinatal Period
Lung
Cardiovascular
Heart Disease
Infant Mortality
Clinical Research
Good Health and Well Being
Blood Flow Velocity
Ebstein Anomaly
Echocardiography
Female
Heart Valve Diseases
Hospital Mortality
Humans
Infant
Newborn
Logistic Models
Male
Perinatal Mortality
Prenatal Diagnosis
Retrospective Studies
Risk Factors
Tricuspid Valve
congenital heart disease
Ebstein anomaly
mortality
neonate
outcome
palliation
right ventricle
tricuspid regurgitation
Cardiorespiratory Medicine and Haematology
Language
Abstract
Background In a recent multicenter study of perinatal outcome in fetuses with Ebstein anomaly or tricuspid valve dysplasia, we found that one third of live-born patients died before hospital discharge. We sought to further describe postnatal management strategies and to define risk factors for neonatal mortality and circulatory outcome at discharge. Methods and Results This 23-center, retrospective study from 2005 to 2011 included 243 fetuses with Ebstein anomaly or tricuspid valve dysplasia. Among live-born patients, clinical and echocardiographic factors were evaluated for association with neonatal mortality and palliated versus biventricular circulation at discharge. Of 176 live-born patients, 7 received comfort care, 11 died