학술논문
A genomic timescale for placental mammal evolution
Document Type
article
Author
Foley, Nicole M; Mason, Victor C; Harris, Andrew J; Bredemeyer, Kevin R; Damas, Joana; Lewin, Harris A; Eizirik, Eduardo; Gatesy, John; Karlsson, Elinor K; Lindblad-Toh, Kerstin; Springer, Mark S; Murphy, William J; Andrews, Gregory; Armstrong, Joel C; Bianchi, Matteo; Birren, Bruce W; Breit, Ana M; Christmas, Matthew J; Clawson, Hiram; Di Palma, Federica; Diekhans, Mark; Dong, Michael X; Fan, Kaili; Fanter, Cornelia; Forsberg-Nilsson, Karin; Garcia, Carlos J; Gazal, Steven; Genereux, Diane P; Goodman, Linda; Grimshaw, Jenna; Halsey, Michaela K; Hickey, Glenn; Hiller, Michael; Hindle, Allyson G; Hubley, Robert M; Hughes, Graham M; Johnson, Jeremy; Juan, David; Kaplow, Irene M; Keough, Kathleen C; Kirilenko, Bogdan; Koepfli, Klaus-Peter; Korstian, Jennifer M; Kowalczyk, Amanda; Kozyrev, Sergey V; Lawler, Alyssa J; Lawless, Colleen; Lehmann, Thomas; Levesque, Danielle L; Li, Xue; Lind, Abigail; Mackay-Smith, Ava; Marinescu, Voichita D; Marques-Bonet, Tomas; Meadows, Jennifer RS; Meyer, Wynn K; Moore, Jill E; Moreira, Lucas R; Moreno-Santillan, Diana D; Morrill, Kathleen M; Muntané, Gerard; Navarro, Arcadi; Nweeia, Martin; Ortmann, Sylvia; Osmanski, Austin; Paten, Benedict; Paulat, Nicole S; Pfenning, Andreas R; Phan, BaDoi N; Pollard, Katherine S; Pratt, Henry E; Ray, David A; Reilly, Steven K; Rosen, Jeb R; Ruf, Irina; Ryan, Louise; Ryder, Oliver A; Sabeti, Pardis C; Schäffer, Daniel E; Serres, Aitor; Shapiro, Beth; Smit, Arian FA; Springer, Mark; Srinivasan, Chaitanya; Steiner, Cynthia; Storer, Jessica M; Sullivan, Kevin AM; Sullivan, Patrick F; Sundström, Elisabeth
Source
Science. 380(6643)
Subject
Language
Abstract
The precise pattern and timing of speciation events that gave rise to all living placental mammals remain controversial. We provide a comprehensive phylogenetic analysis of genetic variation across an alignment of 241 placental mammal genome assemblies, addressing prior concerns regarding limited genomic sampling across species. We compared neutral genome-wide phylogenomic signals using concatenation and coalescent-based approaches, interrogated phylogenetic variation across chromosomes, and analyzed extensive catalogs of structural variants. Interordinal relationships exhibit relatively low rates of phylogenomic conflict across diverse datasets and analytical methods. Conversely, X-chromosome versus autosome conflicts characterize multiple independent clades that radiated during the Cenozoic. Genomic time trees reveal an accumulation of cladogenic events before and immediately after the Cretaceous-Paleogene (K-Pg) boundary, implying important roles for Cretaceous continental vicariance and the K-Pg extinction in the placental radiation.