학술논문

Hospitalizations for Autoimmune Hepatitis Disproportionately Affect Black and Latino Americans
Document Type
article
Source
The American Journal of Gastroenterology. 113(2)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Liver Disease
Genetics
Hepatitis
Clinical Research
Digestive Diseases
Good Health and Well Being
Adult
Black or African American
Ascites
Female
Hepatic Encephalopathy
Hepatitis
Autoimmune
Hispanic or Latino
Hospital Mortality
Hospitalization
Humans
Male
Middle Aged
United States
White People
Young Adult
Gastroenterology & Hepatology
Clinical sciences
Language
Abstract
ObjectivesThe healthcare burden of autoimmune hepatitis (AIH) in the United States has not been characterized. We previously showed that AIH disproportionately affects people of color in a single hospital system. The current study aimed to determine whether the same disparity occurs nationwide.MethodsWe analyzed hospitalizations with a primary discharge diagnosis corresponding to the ICD-9 code for AIH in the National Inpatient Sample between 2008 and 2012. For each racial/ethnic group, we calculated the AIH hospitalization rate per 100,000 population and per 100,000 all-cause hospitalizations, then calculated a risk ratio compared to the reference rate among whites. We used multivariable logistic regression models to assess for racial disparities and to identify predictors of in-hospital mortality during AIH hospitalizations.ResultsThe national rate of AIH hospitalization was 0.73 hospitalizations per 100,000 population. Blacks and Latinos were hospitalized for AIH at a rate 69% (P