학술논문

Acute differences in blood lipids and inflammatory biomarkers following controlled exposures to cookstove air pollution in the STOVES study
Document Type
article
Source
International Journal of Environmental Health Research. 32(3)
Subject
Epidemiology
Health Sciences
Health Effects of Indoor Air Pollution
Health Effects of Household Energy Combustion
Climate-Related Exposures and Conditions
Clinical Research
Good Health and Well Being
Air Pollution
Air Pollution
Indoor
Biomarkers
Cooking
Humans
Lipids
Air pollution
biomass burning
lipoproteins
inflammation
Environmental Sciences
Biological Sciences
Medical and Health Sciences
Environmental & Occupational Health
Human resources and industrial relations
Environmental engineering
Language
Abstract
Household air pollution is a leading risk factor for morbidity and premature mortality. Numerous cookstoves have been developed to reduce household air pollution, but it is unclear whether such cookstoves meaningfully improve health. In a controlled exposure study with a crossover design, we assessed the effect of pollution emitted from multiple cookstoves on acute differences in blood lipids and inflammatory biomarkers. Participants (n = 48) were assigned to treatment sequences of exposure to air pollution emitted from five cookstoves and a filtered-air control. Blood lipids and inflammatory biomarkers were measured before and 0, 3, and 24 hours after treatments. Many of the measured outcomes had inconsistent results. However, compared to control, intercellular adhesion molecule-1 was higher 3 hours after all treatments, and C-reactive protein and serum amyloid-A were higher 24 hours after the highest treatment. Our results suggest that short-term exposure to cookstove air pollution can increase inflammatory biomarkers within 24 hours.