학술논문
Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.
Document Type
article
Author
Quardokus, Ellen; Saunders, Diane; McDonough, Elizabeth; Hickey, John; Werlein, Christopher; Surrette, Christine; Rajbhandari, Presha; Casals, Anna; Tian, Hua; Lowery, Lisa; Neumann, Elizabeth; Björklund, Frida; Neelakantan, Taruna; Croteau, Josh; Wiblin, Anne; Fisher, Jeremy; Livengood, April; Dowell, Karen; Silverstein, Jonathan; Spraggins, Jeffrey; Pryhuber, Gloria; Deutsch, Gail; Ginty, Fiona; Nolan, Garry; Melov, Simon; Jonigk, Danny; Caldwell, Michael; Vlachos, Ioannis; Muller, Werner; Gehlenborg, Nils; Stockwell, Brent; Lundberg, Emma; Germain, Ronald; Camarillo, Jeannie; Kelleher, Neil; Börner, Katy; Radtke, Andrea; Snyder, Michael
Source
Nature Methods. 20(8)
Subject
Language
Abstract
Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Advances in the field now allow high-parameter data collection (>60 targets); however, considerable expertise and capital are needed to construct the antibody panels employed by these methods. Organ mapping antibody panels are community-validated resources that save time and money, increase reproducibility, accelerate discovery and support the construction of a Human Reference Atlas.