학술논문

Patterns of care and outcomes in adolescent and young adult acute lymphoblastic leukemia: a population-based study.
Document Type
article
Source
Blood Advances. 2(8)
Subject
Adolescent
Adult
Community Health Services
Delivery of Health Care
Humans
National Cancer Institute (U.S.)
Pediatrics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Treatment Outcome
United States
Young Adult
Language
Abstract
Adolescents and young adults (AYAs, 15-39 years) with acute lymphoblastic leukemia (ALL) represent a heterogeneous population who receive care in pediatric or adult cancer settings. Using the California Cancer Registry, we describe AYA ALL patterns of care and outcomes over the past decade. Sociodemographics, treatment location, and front-line therapies administered to AYAs diagnosed with ALL between 2004 and 2014 were obtained. Cox regression models evaluated associations between ALL setting and regimen and overall survival (OS) and leukemia-specific survival (LSS) for the entire cohort, younger AYA (